BDBM50574381 CHEMBL4854358

SMILES Cn1cnc2[C@@H](CCc12)NC(=O)c1cn(Cc2ccc(cc2C#N)N2CC3C(C2)C3(F)F)cn1

InChI Key InChIKey=AJULYHREPZHBLX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50574381   

TargetPlasma kallikrein(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574381(CHEMBL4854358)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human plasma kallikrein using H-Pro-Phe-AMC as fluorogenic substrate measured every 2 mins for 12 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed