BDBM50574376 CHEMBL4867704

SMILES Cc1c(Cn2cc(cn2)C(=O)N[C@@H]2CCc3c2ncn3C)cnc(N2CC3CC3C2)c1C#N

InChI Key InChIKey=GQHOJYHITHIAKQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50574376   

TargetPlasma kallikrein(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574376(CHEMBL4867704)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human plasma kallikrein using H-Pro-Phe-AMC as fluorogenic substrate measured every 2 mins for 12 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed