BDBM50574259 CHEMBL4865888

SMILES CC(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O

InChI Key InChIKey=JFVISPBLQYTSHU-UHFFFAOYSA-N

Data  6 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50574259   

TargetMelanocortin receptor 3(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50574259(CHEMBL4865888)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mouse MC3R expressed in HEK293 cells assessed as induction of cAMP level incubated for 2 hr by alphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50574259(CHEMBL4865888)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mouse MC5R expressed in HEK293 cells assessed as induction of cAMP level at 100 uM incubated for 2 hr by alphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50574259(CHEMBL4865888)
Affinity DataKi:  1nMAssay Description:Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50574259(CHEMBL4865888)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to mouse MC4R expressed in HEK293 cells assessed as inhibition constant by schild plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMelanocortin receptor 3(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50574259(CHEMBL4865888)
Affinity DataKi:  16nMAssay Description:Antagonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50574259(CHEMBL4865888)
Affinity DataKi:  20nMAssay Description:Binding affinity to mouse MC1R expressed in HEK293 cells assessed as inhibition constant by schild plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMelanocortin receptor 3(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50574259(CHEMBL4865888)
Affinity DataKi:  32nMAssay Description:Binding affinity to mouse MC3R expressed in HEK293 cells assessed as inhibition constant by schild plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMelanocortin receptor 5(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50574259(CHEMBL4865888)
Affinity DataKi:  250nMAssay Description:Binding affinity to mouse MC5R expressed in HEK293 cells assessed as inhibition constant by schild plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed