BDBM50573802 CHEMBL4875913

SMILES CN1CCN(CC1)c1ccc(Nc2ncc(Cl)c(Nc3cccc(c3)C(F)(F)F)n2)cn1

InChI Key InChIKey=YNGWEWBJFQRFCH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50573802   

TargetDipeptidyl peptidase 1(Human)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50573802(CHEMBL4875913)
Affinity DataIC50: 136nMAssay Description:Inhibition of human recombinant Cathepsin C using H-Gly-Arg-AMC as substrate pretreated for 30 mins followed by substrate addition incubated for 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetDipeptidyl peptidase 1(Human)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50573802(CHEMBL4875913)
Affinity DataIC50: 82nMAssay Description:Inhibition of human Cathepsin C in human THP-1 cells using H-Gly-Phe-AFC as substrate pretreated for 60 mins followed by substrate addition incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetDipeptidyl peptidase 1(Human)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50573802(CHEMBL4875913)
Affinity DataIC50: 96nMAssay Description:Inhibition of human Cathepsin C in human U-937 cells using H-Gly-Phe-AFC as substrate pretreated for 60 mins followed by substrate addition incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed