BDBM50573717 CHEMBL4854730

SMILES COc1cc2C3CC(O)C(CC(C)C)CN3CCc2cc1OCC(F)(F)F

InChI Key InChIKey=JXFGMMABBUBPCW-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50573717   

TargetSynaptic vesicular amine transporter(Rat)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50573717(CHEMBL4854730)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetSynaptic vesicular amine transporter(Rat)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50573717(CHEMBL4854730)
Affinity DataIC50: 6nMAssay Description:Inhibition of [3H]DA uptake at VMAT2 in rat striatal synaptosome incubated for 10 mins followed by [3H]DA addition and measured after 20 mins by TopC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50573717(CHEMBL4854730)
Affinity DataIC50: 6.51E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50573717(CHEMBL4854730)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50573717(CHEMBL4854730)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50573717(CHEMBL4854730)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50573717(CHEMBL4854730)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50573717(CHEMBL4854730)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2B6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed