BDBM50573480 CHEMBL4869328

SMILES O=C1NCCC11CCN(CC1)c1c(cnc2[nH]ccc12)-c1ccc2[nH]cnc2c1

InChI Key InChIKey=DWRDPMAVWSBVOL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50573480   

TargetCyclin-C(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50573480(CHEMBL4869328)
Affinity DataIC50: 5nMAssay Description:Inhibition of tracer 236 binding to recombinant human His-tagged full length CDK8/Cyclin C expressed in baculovirus expression system by Lanthascreen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50573480(CHEMBL4869328)
Affinity DataIC50: 17nMAssay Description:Inhibition of tracer 236 binding to recombinant human GST/His-tagged CDK11 (1 to 502 residues)/Cyclin C( 1 to 283 residues) expressed in insect cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed