BDBM50573455 CHEMBL4848064

SMILES CNC(=O)N1N=C(c2ccc(cc2)N2CCN(CC2)C(=O)CCCCNC(=O)COc2cccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c23)c2cc(OC)c(OC)cc2C[C@@H]1C

InChI Key InChIKey=MQPRRCLCHOSXND-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50573455   

TargetBromodomain-containing protein 4(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50573455(CHEMBL4848064)
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant human His-tagged BRD4 BD1 using biotin-labelled histone H4 acetylated peptide as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50573455(CHEMBL4848064)
Affinity DataIC50: 118nMAssay Description:Inhibition of recombinant human His-tagged BRD4 BD2 using biotin-labelled histone H4 acetylated peptide as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50573455(CHEMBL4848064)
Affinity DataIC50: 34nMAssay Description:Inhibition of His6-tagged recombinant human BRD4 BD1 using (SGRGK(Ac)GGK(Ac)GLGK(Ac)GGAK(Ac)RHGSGSK-biotin) as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50573455(CHEMBL4848064)
Affinity DataIC50: 118nMAssay Description:Inhibition of His6-tagged recombinant human BRD4 BD2 using (SGRGK(Ac)GGK(Ac)GLGK(Ac)GGAK(Ac)RHGSGSK-biotin) as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed