BDBM50573354 CHEMBL4854800

SMILES FC(F)CN1Cc2cc(ncc2C2=CN=C(NCc3c4CCOc4ccc3F)N3C=NC(C23)C1=O)C(F)(F)F

InChI Key InChIKey=VTJYPZHCSHQJME-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50573354   

TargetPolycomb protein EED(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50573354(CHEMBL4854800)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50573354(CHEMBL4854800)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50573354(CHEMBL4854800)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2B6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50573354(CHEMBL4854800)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50573354(CHEMBL4854800)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50573354(CHEMBL4854800)
Affinity DataIC50: 1.89E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50573354(CHEMBL4854800)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50573354(CHEMBL4854800)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by manual-patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed