BDBM50573273 CHEMBL4862150

SMILES CC1(C)CCC(CN2CCN(CC2)c2ccc(C(=O)NS(=O)(=O)c3ccc(NCC4CCOC4)c(c3)[N+]([O-])=O)c(Oc3cnc4[nH]ccc4c3)c2)=C(C1)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=ZHLMZMGUSDYXJC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50573273   

TargetApoptosis regulator Bcl-2(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50573273(CHEMBL4862150)
Affinity DataIC50: 4.70nMAssay Description:Displacement of Bak derived peptide from Bcl-2 (unknown origin) measured after 15 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50573273(CHEMBL4862150)
Affinity DataIC50: 897nMAssay Description:Displacement of Bak derived peptide from Bcl-xL (unknown origin) measured after 15 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed