BDBM50573271 CHEMBL4858569

SMILES CN1CCC(CNc2ccc(cc2[N+]([O-])=O)S(=O)(=O)NC(=O)c2ccc(cc2Oc2cnc3[nH]ccc3c2)N2CCN(CC3=C(CC(C)(C)CC3)c3ccc(cc3)C(F)(F)F)CC2)C1

InChI Key InChIKey=KNGQPRZPODEMOV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50573271   

TargetApoptosis regulator Bcl-2(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50573271(CHEMBL4858569)
Affinity DataIC50: 2.40nMAssay Description:Displacement of Bak derived peptide from Bcl-2 (unknown origin) measured after 15 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50573271(CHEMBL4858569)
Affinity DataIC50: 36nMAssay Description:Displacement of Bak derived peptide from Bcl-xL (unknown origin) measured after 15 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed