BDBM50573149 CHEMBL4879167

SMILES CN(C)Cc1ccc(nc1)-c1cnc2ccc(CN(C)c3nnc(o3)-c3ncc(cc3C)-c3c(C)nn(C)c3C)cn12

InChI Key InChIKey=BFKCQNVNPUJABZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50573149   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50573149(CHEMBL4879167)
Affinity DataIC50: 13nMAssay Description:Inhibition of FLAG-tagged MER (unknown origin) transfected in Cos-7cells assessed as phosphorylation level incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50573149(CHEMBL4879167)
Affinity DataIC50: 126nMAssay Description:Inhibition of FLAG-tagged AXL (unknown origin) transfected in Cos-7 cells assessed as phosphorylation level incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50573149(CHEMBL4879167)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of FLAG-tagged FLT3 (unknown origin) transfected in Cos-7 cells assessed as phosphorylation level incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50573149(CHEMBL4879167)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of FLAG-tagged Tyro3 (unknown origin) transfected in Cos-7 cells assessed as phosphorylation level incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed