BDBM50573109 CHEMBL4846672

SMILES COc1cc(cn2ncnc12)-c1cc(C)c2c(c1)[nH]c1ccc(cc21)C1CCNCC1

InChI Key InChIKey=LRRFBDGKLSPYPM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50573109   

TargetToll-like receptor 7(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50573109(CHEMBL4846672)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human TLR7 in HEK-Blue hTLR7 cells assessed as reduction in gardiquimod-activated NF-KappaB by SEAP reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50573109(CHEMBL4846672)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human TLR8 in HEK-Blue hTLR8 cells assessed as reduction in R848-activated NF-KappaB by SEAP reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetToll-like receptor 9(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50573109(CHEMBL4846672)
Affinity DataIC50: 153nMAssay Description:Inhibition of human TLR9 in HEK-Blue hTLR9 cells assessed as reduction in ODN2006-activated NF-KappaB by SEAP reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed