BDBM50573101 CHEMBL4861467

SMILES CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC11CCN(CC2CC2)CC1)c1ncc([nH]1)-c1cc2cccnc2cc1OC

InChI Key InChIKey=LBLZRRPKVKWPQM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50573101   

TargetHistone deacetylase 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50573101(CHEMBL4861467)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of human recombinant FLAG-tagged HDAC1 expressed in HEK293F cells incubated for 30 mins by Fluor De Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50573101(CHEMBL4861467)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human recombinant FLAG-tagged HDAC2 expressed in Sf9 cells incubated for 30 mins by Fluor De Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50573101(CHEMBL4861467)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human recombinant FLAG-tagged HDAC3 expressed in HEK293F cells incubated for 30 mins by Fluor De Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50573101(CHEMBL4861467)
Affinity DataIC50: 76nMAssay Description:Inhibition of human HDAC6 incubated for 30 mins by Fluor De Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed