BDBM50573064 CHEMBL4854969

SMILES CNc1nc(Nc2ccc(OC(F)(F)F)cc2)nc(n1)-c1ccc(OC)cc1

InChI Key InChIKey=MRKBZWPHEVZQHH-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50573064   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50573064(CHEMBL4854969)
Affinity DataEC50:  3.00E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in Ach-induced current at -90 mV membra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50573064(CHEMBL4854969)
Affinity DataEC50:  3.02E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in 100 uM Ach-induced current at -90 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed