BDBM50572965 CHEMBL4875218

SMILES CN1CCCN(CC1)S(=O)(=O)c1cc(NC(=O)Cn2ncc(Cl)c(Cl)c2=O)ccc1C

InChI Key InChIKey=HMSYSGKNOIHRNA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50572965   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
The Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50572965(CHEMBL4875218)
Affinity DataIC50: 5.40E+3nMAssay Description:Displacement of fluorophore-labeled RIOK1 from human PRMT5/WDR77 hetero octameric complex expressed in Sf9 cells by competition fluorescence polariza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed