BDBM50572864 CHEMBL4860312

SMILES CNC(=O)C(C)N(CC(O)(c1ccccc1)c1ccccc1)C(=O)c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=RJGIXXZQQPSUGA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50572864   

TargetBromodomain-containing protein 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50572864(CHEMBL4860312)
Affinity DataIC50: 40nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-tagged BRD4 BD2/BD1 Y97A mutant (1 to 477 residue) (unknown origin) measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50572864(CHEMBL4860312)
Affinity DataIC50: 1.26E+3nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-tagged BRD4 BD1/BD2 Y390A mutant (1 to 477 residue) (unknown origin) measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed