BDBM50572669 CHEMBL4859758

SMILES Cn1ccc2cc(CNC(=O)N3CC(COc4ccc(cc4)C(F)(F)F)C3)ccc12

InChI Key InChIKey=AXWYGYRYNQEVTC-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50572669   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50572669(CHEMBL4859758)
Affinity DataEC50:  80nMAssay Description:Positive allosteric modulator activity at human alpha7 nAChR expressed in Flp-In-HEK293 cells co-expressing RIC-3 assessed as potentiation of PNU2829...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50572669(CHEMBL4859758)
Affinity DataEC50:  80nMAssay Description:Positive allosteric modulator activity at human alpha7 nAChR expressed in Flp-In HEK293 cells assessed as increase in calcium influx incubated for 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed