BDBM50572434 CHEMBL4861780

SMILES CC(C)n1ncc2cc(Nc3ncnc4c(F)c(F)ccc34)ccc12

InChI Key InChIKey=CABCUURODQCKED-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50572434   

TargetATP-dependent translocase ABCB1(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50572434(CHEMBL4861780)Copy SMILESCopy InChI

Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition of ABCB1 (unknown origin) expressed in A2780/ADR cells preincubated for 30 mins followed by calcein AM addition and measured at 60 secs ti...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/22/2022
Entry Details Article
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TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50572434(CHEMBL4861780)Copy SMILESCopy InChI

Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in MDCK2-BCRP cells assessed as reduction in pheophorbide A accumulation measured after 120 mins by fl...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/22/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL