BDBM50572433 CHEMBL4879245

SMILES CCN(c1ccccc1)c1cc(NCCc2nnc(s2)C(C)C)ncn1

InChI Key InChIKey=LMKXMZWSBUBRSX-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50572433   

TargetATP-dependent translocase ABCB1(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50572433(CHEMBL4879245)Copy SMILESCopy InChI

Affinity DataIC50: 3.27E+4nMAssay Description:Inhibition of ABCB1 (unknown origin) expressed in A2780/ADR cells preincubated for 30 mins followed by calcein AM addition and measured at 60 secs ti...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/22/2022
Entry Details Article
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TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50572433(CHEMBL4879245)Copy SMILESCopy InChI

Affinity DataIC50: 1.74E+4nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in MDCK2-BCRP cells assessed as reduction in pheophorbide A accumulation measured after 120 mins by fl...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/22/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL