BDBM50572192 CHEMBL4858549

SMILES COc1ccc2nccc(CCN3CCC(CC3)NCc3ccc(Br)cc3)c2n1

InChI Key InChIKey=KFEYIAJIUJJIRU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50572192   

TargetDNA gyrase subunit A/B(Staphylococcus aureus)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50572192(CHEMBL4858549)
Affinity DataIC50: 570nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50572192(CHEMBL4858549)
Affinity DataIC50: 26nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50572192(CHEMBL4858549)
Affinity DataIC50: 7.22E+3nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using supercoiled pNO1 plasmid DNA as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed