BDBM50572127 CHEMBL4850335

SMILES Cc1cc2c(cnc(NC3CCN(CCCN)CC3)c2[nH]c1=O)C1=CCOCC1

InChI Key InChIKey=QZOBWRFYLHQNFG-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50572127   

TargetTranscription initiation factor TFIID subunit 1(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50572127(CHEMBL4850335)
Affinity DataIC50: 32nMAssay Description:Inhibition of TAF1 bromodomain 2 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50572127(CHEMBL4850335)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50572127(CHEMBL4850335)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of ATAD2 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetTranscription initiation factor TFIID subunit 1(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50572127(CHEMBL4850335)
Affinity DataKi:  0.398nMAssay Description:Inhibition of human partial length TAF1 bromodomain 2 (D1521 to D1656 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50572127(CHEMBL4850335)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of human partial length BRD4 BD1 (N44 to E168 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed