BDBM50571957 CHEMBL1643349

SMILES CC1(C)C(=O)Nc2ccccc12

InChI Key InChIKey=KEZHRKOVLKUYCQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50571957   

LigandPNGBDBM50571957(CHEMBL1643349)
Affinity DataIC50: 5.02E+4nMAssay Description:Inhibition of human PDHK2 assessed as reduction in acetyl-coenzymeA formation by RapidFire mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571957(CHEMBL1643349)
Affinity DataIC50: 8.90E+5nMAssay Description:Inhibition of human PDHK4 assessed as reduction in acetyl-coenzymeA formation by RapidFire mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571957(CHEMBL1643349)
Affinity DataIC50: 2.79E+5nMAssay Description:Inhibition of human PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
LigandPNGBDBM50571957(CHEMBL1643349)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed