BDBM50571922 CHEMBL4850126

SMILES COc1ccc(F)c(CN2C(=O)Cc3c2nc(N)nc3Cl)c1F

InChI Key InChIKey=GYCXQPDCHIDSOF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50571922   

TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50571922(CHEMBL4850126)
Affinity DataIC50: 230nMAssay Description:Inhibition of PU-H71-FITC3 binding to recombinant full length TRAP1 (unknown origin) incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50571922(CHEMBL4850126)
Affinity DataIC50: 893nMAssay Description:Inhibition of PU-H71-FITC3 binding to recombinant N-terminal HSP90alpha (unknown origin) incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetEndoplasmin(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50571922(CHEMBL4850126)
Affinity DataIC50: 649nMAssay Description:Inhibition of PU-H71-FITC3 binding to recombinant N-terminal Grp94 (unknown origin) incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed