BDBM50571896 CHEMBL4869481

SMILES c1c(c(cc2c1OCO2)Br)Cn3c4c(c(nc(n4)N)Cl)nc3O

InChI Key InChIKey=JGUUSDOBVPWHAQ-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50571896   

TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50571896(CHEMBL4869481)
Affinity DataIC50: 66nMAssay Description:Inhibition of PU-H71-FITC3 binding to recombinant full length TRAP1 (unknown origin) incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50571896(CHEMBL4869481)
Affinity DataIC50: 394nMAssay Description:Inhibition of PU-H71-FITC3 binding to recombinant N-terminal HSP90alpha (unknown origin) incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetEndoplasmin(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50571896(CHEMBL4869481)
Affinity DataIC50: 194nMAssay Description:Inhibition of PU-H71-FITC3 binding to recombinant N-terminal Grp94 (unknown origin) incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50571896(CHEMBL4869481)
Affinity DataIC50: 66nMAssay Description:Inhibition of TRAP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50571896(CHEMBL4869481)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of TRAP1 NTD (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)