BDBM50571889 CHEMBL4857086

SMILES [H][C@@]1(CC[C@@H](CC1)c1cccc(C)n1)[C@@H](CC)NC(=O)c1ccc(Cl)cc1

InChI Key InChIKey=HOTAARNYDWLVIM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50571889   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50571889(CHEMBL4857086)
Affinity DataIC50: 48nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells preincubated for 2 hrs followed by recombinant human IFNgamma stimulation and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
Bristol Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50571889(CHEMBL4857086)
Affinity DataIC50: 121nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by recombinant murine IFNgamma stimulation and measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed