BDBM50571856 CHEMBL4850551

SMILES CCC(C)(NC(=O)c1cc(F)cc2cc(oc12)-c1ccc(Cl)cc1)C(O)=O

InChI Key InChIKey=ATBPUXQNMPYSAT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50571856   

TargetEndoplasmic reticulum aminopeptidase 1(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50571856(CHEMBL4850551)
Affinity DataIC50: 377nMAssay Description:Inhibition of wild type ERAP1 (unknown origin) using L-Rho-Succ-FKARKF as substrate preincubated for 15 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50571856(CHEMBL4850551)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50571856(CHEMBL4850551)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using testosterone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50571856(CHEMBL4850551)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of ERAP2 (unknown origin) using Arg-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50571856(CHEMBL4850551)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of APN (unknown origin) using Ala-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed