BDBM50571773 CHEMBL4869232

SMILES ONC(=O)c1ccc(CSc2nnc(-c3ccncc3)n2CC=C)cc1

InChI Key InChIKey=ZLWNIOZDEQOURO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50571773   

TargetHistone deacetylase 1(Human)
Minia University

Curated by ChEMBL
LigandPNGBDBM50571773(CHEMBL4869232)
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of human full-length recombinant HDAC1 preincubated for 5 mins followed by HDAC substrate addition and further incubated for 45 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Minia University

Curated by ChEMBL
LigandPNGBDBM50571773(CHEMBL4869232)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of human full-length recombinant HDAC2 preincubated for 5 mins followed by HDAC substrate addition and further incubated for 45 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Minia University

Curated by ChEMBL
LigandPNGBDBM50571773(CHEMBL4869232)
Affinity DataIC50: 2.07E+4nMAssay Description:Inhibition of human full-length recombinant HDAC3 preincubated for 5 mins followed by HDAC substrate addition and further incubated for 45 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Minia University

Curated by ChEMBL
LigandPNGBDBM50571773(CHEMBL4869232)
Affinity DataIC50: 9.86E+3nMAssay Description:Inhibition of human full-length recombinant HDAC6 preincubated for 5 mins followed by HDAC substrate addition and further incubated for 45 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Minia University

Curated by ChEMBL
LigandPNGBDBM50571773(CHEMBL4869232)
Affinity DataIC50: 2.84E+4nMAssay Description:Inhibition of human full-length recombinant C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cells preincubated for 5 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Minia University

Curated by ChEMBL
LigandPNGBDBM50571773(CHEMBL4869232)
Affinity DataIC50: 4.61E+4nMAssay Description:Inhibition of FAK (unknown origin) by FRET-based Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed