BDBM50571765 CHEMBL4860240

SMILES ONC(=O)CCCCCSc1nnc(-c2ccncc2)n1CC=C

InChI Key InChIKey=YBHOPFXYPZVHFF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50571765   

TargetHistone deacetylase 1(Human)
Minia University

Curated by ChEMBL
LigandPNGBDBM50571765(CHEMBL4860240)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human full-length recombinant HDAC1 preincubated for 5 mins followed by HDAC substrate addition and further incubated for 45 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Minia University

Curated by ChEMBL
LigandPNGBDBM50571765(CHEMBL4860240)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of human full-length recombinant HDAC2 preincubated for 5 mins followed by HDAC substrate addition and further incubated for 45 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Minia University

Curated by ChEMBL
LigandPNGBDBM50571765(CHEMBL4860240)
Affinity DataIC50: 2.22E+5nMAssay Description:Inhibition of human full-length recombinant HDAC3 preincubated for 5 mins followed by HDAC substrate addition and further incubated for 45 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Minia University

Curated by ChEMBL
LigandPNGBDBM50571765(CHEMBL4860240)
Affinity DataIC50: 2.88E+5nMAssay Description:Inhibition of human full-length recombinant HDAC6 preincubated for 5 mins followed by HDAC substrate addition and further incubated for 45 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Minia University

Curated by ChEMBL
LigandPNGBDBM50571765(CHEMBL4860240)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of human full-length recombinant C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cells preincubated for 5 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Minia University

Curated by ChEMBL
LigandPNGBDBM50571765(CHEMBL4860240)
Affinity DataIC50: 1.89E+5nMAssay Description:Inhibition of FAK (unknown origin) by FRET-based Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed