BDBM50571229 CHEMBL4852178::US12227515, Compound EJR-876-35

SMILES N=C1c2sc(cc2C(=O)NC1=O)-c1ccc(OCCCCNC(=O)CC23CC4CC(CC(C4)C2)C3)cc1

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50571229   

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50571229(CHEMBL4852178 | US12227515, Compound EJR-876-35)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of recombinant human PTP4A3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50571229(CHEMBL4852178 | US12227515, Compound EJR-876-35)
Affinity DataIC50: 643nMAssay Description:Table 2: Recombinant human PTP4A3 phosphatase was used and the enzymatic assay was performed as previously described,20 except that it was fully auto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50571229(CHEMBL4852178 | US12227515, Compound EJR-876-35)
Affinity DataIC50: 643nMAssay Description:Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black small volume microtiter plates, as previously described using r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent