BDBM50571032 CHEMBL4848010::US12415803, Example 101

SMILES CC(C)(C)c1noc(C(=O)NC2CCCc3cc(-c4ccnc5[nH]c(-c6cnn(C7CCOCC7)c6)nc45)ccc32)n1

InChI Key InChIKey=WHASZSIQSYUKGT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50571032   

TargetTyrosine-protein kinase BTK(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50571032BDBM50571032(CHEMBL4848010 | US12415803, Example 101)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50571032BDBM50571032(CHEMBL4848010 | US12415803, Example 101)
Affinity DataIC50: 5.5nMAssay Description:The following describes a microfluidic, off-chip mobility shift kinase assay used to measure inherent potency of compounds against BTK enzyme. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50571032BDBM50571032(CHEMBL4848010 | US12415803, Example 101)
Affinity DataIC50: 51nMAssay Description:Inhibition of BTK in human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed