BDBM50570895 CHEMBL4859276

SMILES OC(=O)C(=C)CC(O)(C(O)=O)C(F)(F)F

InChI Key InChIKey=BXEDABZIAFVUQI-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50570895   

TargetMethylcytosine dioxygenase TET2(Human)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570895(CHEMBL4859276)
Affinity DataIC50: 1.08E+5nMAssay Description:Inhibition of recombinant human GST-tagged TET2 (1099 to 1936 residues) expressed in Escherichia coli BL21 (DE3)pLysS assessed as reduction in 5hmc l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMethylcytosine dioxygenase TET2(Human)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570895(CHEMBL4859276)
Affinity DataKd:  2.05E+3nMAssay Description:Binding affinity to human recombinant TET2 (1099 to 1936) catalytic domain assessed as dissociation constant by micro-scale thermophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed