BDBM50570894 CHEMBL4855677

SMILES CC(O)(CC(=C)C(O)=O)C(O)=O

InChI Key InChIKey=MTKAWYCBZAZECN-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50570894   

TargetMethylcytosine dioxygenase TET2(Human)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570894(CHEMBL4855677)
Affinity DataIC50: 5.48E+4nMAssay Description:Inhibition of recombinant human GST-tagged TET2 (1099 to 1936 residues) expressed in Escherichia coli BL21 (DE3)pLysS assessed as reduction in 5hmc l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMethylcytosine dioxygenase TET2(Human)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570894(CHEMBL4855677)
Affinity DataKd:  610nMAssay Description:Binding affinity to human recombinant TET2 (1099 to 1936) catalytic domain assessed as dissociation constant by micro-scale thermophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed