BDBM50570893 CHEMBL4851104

SMILES OC(CC(=C)C(O)=O)C(O)=O

InChI Key InChIKey=UEBQCRUWROCTOK-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50570893   

TargetMethylcytosine dioxygenase TET2(Human)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570893(CHEMBL4851104)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of recombinant human GST-tagged TET2 (1099 to 1936 residues) expressed in Escherichia coli BL21 (DE3)pLysS assessed as reduction in 5hmc l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMethylcytosine dioxygenase TET1(Human)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570893(CHEMBL4851104)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant human N-terminal Flag-tagged TET1 (1418 to 2136 residues) expressed in Baculovirus infected Sf9 cells assessed as reduction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMethylcytosine dioxygenase TET3(Human)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570893(CHEMBL4851104)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of recombinant human N-terminal Flag-tagged C-terminal His-tagged TET3 (824 to 1795 residues) expressed in Baculovirus infected Sf9 cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMethylcytosine dioxygenase TET2(Human)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570893(CHEMBL4851104)
Affinity DataKd:  300nMAssay Description:Binding affinity to human recombinant TET2 (1099 to 1936) catalytic domain assessed as dissociation constant by micro-scale thermophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed