BDBM50570879 CHEMBL4859626

SMILES COc1ccc(cc1)-c1nn(cc1\C=C\c1cc(C(=O)N2CCOCC2)c2cc(Cl)ccc2n1)-c1ccc(Cl)cc1

InChI Key InChIKey=UTIFXRVYZVJPBY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50570879   

TargetProstaglandin G/H synthase 1(Sheep)
Zagazig University

Curated by ChEMBL
LigandPNGBDBM50570879(CHEMBL4859626)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate preincubated with enzyme for 5 mins followed by incubation with substrate for 5 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Zagazig University

Curated by ChEMBL
LigandPNGBDBM50570879(CHEMBL4859626)
Affinity DataIC50: 100nMAssay Description:Inhibition of ovine COX-2 using arachidonic acid as substrate preincubated with enzyme for 5 mins followed by incubation with substrate for 5 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed