BDBM50570878 CHEMBL4848763

SMILES COc1ccc(cc1)-c1cc(-c2nnc(SC\C(=N\O)c3ccccc3)n2-c2ccccc2)c2ccccc2n1

InChI Key InChIKey=ZTYYHSDNSPVFDS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50570878   

TargetProstaglandin G/H synthase 1(Sheep)
Zagazig University

Curated by ChEMBL
LigandPNGBDBM50570878(CHEMBL4848763)
Affinity DataIC50: 480nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate preincubated with enzyme for 20 mins followed by incubation with substrate for 2 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandPNGBDBM50570878(CHEMBL4848763)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated with enzyme for 20 mins followed by incubation with substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed