BDBM50570865 CHEMBL4867950

SMILES Oc1nc2ccc(OCc3ccccc3)cc2cc1\C=N\n1c(=S)[nH]nc(Cc2ccccc2)c1=O

InChI Key InChIKey=YGFBHDLSZNZFIU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50570865   

TargetProstaglandin G/H synthase 1(Sheep)
Zagazig University

Curated by ChEMBL
LigandPNGBDBM50570865(CHEMBL4867950)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate preincubated with enzyme for 5 mins followed by substrate addition by colorimetric anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandPNGBDBM50570865(CHEMBL4867950)
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated with enzyme for 5 mins followed by substrate addition by color...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed