BDBM50570857 CHEMBL4868525

SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(O)=O

InChI Key InChIKey=WIDHYNXMVQSJAN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50570857   

TargetMitogen-activated protein kinase 14(Human)
Carna Biosciences

Curated by ChEMBL
LigandPNGBDBM50570857(CHEMBL4868525)
Affinity DataIC50: 1.30nMAssay Description:Binding affinity to P38alpha MAPK (unknown origin) using Smad3 as substrate incubated for 1 hr in presence of ATP by ELISA based competitive binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Carna Biosciences

Curated by ChEMBL
LigandPNGBDBM50570857(CHEMBL4868525)
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity to recombinant human N-terminal GST-tagged P38alpha MAPK expressed in Escherichia coli using ERKtide as substrate by mobility shift ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Carna Biosciences

Curated by ChEMBL
LigandPNGBDBM50570857(CHEMBL4868525)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to P38alpha MAPK (unknown origin) using MBP as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Carna Biosciences

Curated by ChEMBL
LigandPNGBDBM50570857(CHEMBL4868525)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to P38alpha MAPK (unknown origin) using MAPKAPK2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed