BDBM50570681 CHEMBL4870513

SMILES COc1cc(Nc2nc(NCc3cccc(NC(=O)CCl)c3)n3ccnc3c2C(N)=O)cc(OC)c1

InChI Key InChIKey=LRSSMJXTQUVHEA-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50570681   

TargetTyrosine-protein kinase ZAP-70(Human)
University of Chinese Academy of Science

Curated by ChEMBL
LigandPNGBDBM50570681(CHEMBL4870513)
Affinity DataIC50: 55nMAssay Description:Inhibition of N-terminal GST-fused human recombinant full length ZAP70 (1 to 619 residues) expressed in baculovirus-infected Sf21 cells using FAM-22 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
University of Chinese Academy of Science

Curated by ChEMBL
LigandPNGBDBM50570681(CHEMBL4870513)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal GST-fused human recombinant full length SYK (1 to 635 residues) expressed in baculovirus-infected Sf21 cells using FAM-22 pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Chinese Academy of Science

Curated by ChEMBL
LigandPNGBDBM50570681(CHEMBL4870513)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ABL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
University of Chinese Academy of Science

Curated by ChEMBL
LigandPNGBDBM50570681(CHEMBL4870513)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
University of Chinese Academy of Science

Curated by ChEMBL
LigandPNGBDBM50570681(CHEMBL4870513)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
University of Chinese Academy of Science

Curated by ChEMBL
LigandPNGBDBM50570681(CHEMBL4870513)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ITK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
University of Chinese Academy of Science

Curated by ChEMBL
LigandPNGBDBM50570681(CHEMBL4870513)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
University of Chinese Academy of Science

Curated by ChEMBL
LigandPNGBDBM50570681(CHEMBL4870513)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
University of Chinese Academy of Science

Curated by ChEMBL
LigandPNGBDBM50570681(CHEMBL4870513)
Affinity DataIC50: 562nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
University of Chinese Academy of Science

Curated by ChEMBL
LigandPNGBDBM50570681(CHEMBL4870513)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Chinese Academy of Science

Curated by ChEMBL
LigandPNGBDBM50570681(CHEMBL4870513)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
University of Chinese Academy of Science

Curated by ChEMBL
LigandPNGBDBM50570681(CHEMBL4870513)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
University of Chinese Academy of Science

Curated by ChEMBL
LigandPNGBDBM50570681(CHEMBL4870513)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SYK (unknown origin) using ULight-TK peptide as substrate incubated for 120 mins in presence of ATP by Lance Ultra Kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
University of Chinese Academy of Science

Curated by ChEMBL
LigandPNGBDBM50570681(CHEMBL4870513)
Affinity DataIC50: 45nMAssay Description:Inhibition of ZAP-70 (unknown origin) using ULight-TK peptide as substrate incubated for 120 mins in presence of ATP by Lance Ultra Kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed