BDBM50570456 CHEMBL4867978

SMILES Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc(CCN3CCOCC3)cc2)CC1

InChI Key InChIKey=BTEMXIHCAGOPHX-UHFFFAOYSA-N

Data  9 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50570456   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50570456(CHEMBL4867978)
Affinity DataIC50: 2.41E+3nMAssay Description:Inhibition of human ERG by automated patch method relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50570456(CHEMBL4867978)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at D2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50570456(CHEMBL4867978)
Affinity DataIC50: 64nMAssay Description:Antagonist activity at D3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50570456(CHEMBL4867978)
Affinity DataIC50: 247nMAssay Description:Antagonist activity at 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50570456(CHEMBL4867978)
Affinity DataIC50: 186nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50570456(CHEMBL4867978)
Affinity DataIC50: 28nMAssay Description:Antagonist activity at histamine H3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50570456(CHEMBL4867978)
Affinity DataIC50: 348nMAssay Description:Antagonist activity at 5-HT6 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50570456(CHEMBL4867978)
Affinity DataKi:  5.60nMAssay Description:Binding affinity to 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50570456(CHEMBL4867978)
Affinity DataKi:  8.40nMAssay Description:Binding affinity to 5-HT2A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50570456(CHEMBL4867978)
Affinity DataKi:  9.60nMAssay Description:Binding affinity to dopamine D3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50570456(CHEMBL4867978)
Affinity DataKi:  11nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50570456(CHEMBL4867978)
Affinity DataKi:  14nMAssay Description:Binding affinity to histamine H3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50570456(CHEMBL4867978)
Affinity DataKi:  141nMAssay Description:Binding affinity to 5-HT6 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50570456(CHEMBL4867978)
Affinity DataKi:  438nMAssay Description:Binding affinity to alpha1 adrenoceptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50570456(CHEMBL4867978)
Affinity DataKi:  610nMAssay Description:Binding affinity to 5-HT2C receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50570456(CHEMBL4867978)
Affinity DataKi:  968nMAssay Description:Binding affinity to histamine H1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed