BDBM50570051 CHEMBL4874696

SMILES CC(=O)NCCNCc1cc(Cl)c(OCc2cccc(c2C)-c2cccc3N(CCCN4CCC(O)CC4)CCc23)cc1OCc1cncc(c1)C#N

InChI Key InChIKey=PKWDNCUAQKMUSZ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50570051   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50570051(CHEMBL4874696)
Affinity DataEC50:  430nMAssay Description:Inhibition of PD-1/PD-L1 interaction in CHO cells expressing PD-Ll/TCR cocultured with human Jurkat cells expressing PD-1 assessed as activation of e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50570051(CHEMBL4874696)
Affinity DataIC50: 17nMAssay Description:Inhibition of PD1 (unknown origin)/PDL1 (unknown origin) protein-protein interaction by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed