BDBM50569855 CHEMBL4851134

SMILES O=S(=O)(N[C@H]1CCCC[C@@H]1N1CCc2ccccc2C1)c1ccccc1

InChI Key InChIKey=UHOANONOOFZNKU-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50569855   

TargetMucolipin-1(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50569855(CHEMBL4851134)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of human TRPML1deltaNC-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMucolipin-2(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50569855(CHEMBL4851134)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of human TRPML2-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMucolipin-3(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50569855(CHEMBL4851134)
Affinity DataEC50:  9.50E+3nMAssay Description:Activation of human TRPML3-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed