BDBM50569851 CHEMBL4870275

SMILES Cc1ccc(CN2CCN(CC2)[C@H]2CCCC[C@@H]2NS(=O)(=O)c2ccccc2)cc1

InChI Key InChIKey=YLZOEYZPTAYOIS-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50569851   

TargetMucolipin-1(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50569851(CHEMBL4870275)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human TRPML1deltaNC-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMucolipin-2(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50569851(CHEMBL4870275)
Affinity DataEC50:  4.40E+3nMAssay Description:Activation of human TRPML2-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMucolipin-3(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50569851(CHEMBL4870275)
Affinity DataEC50:  5.80E+3nMAssay Description:Activation of human TRPML3-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed