BDBM50569846 CHEMBL4857820

SMILES COc1ccccc1N1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccc(C)cc1

InChI Key InChIKey=VPAVKZJYIQXFHA-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50569846   

TargetMucolipin-1(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50569846(CHEMBL4857820)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human TRPML1deltaNC-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMucolipin-2(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50569846(CHEMBL4857820)
Affinity DataEC50:  4.00E+3nMAssay Description:Activation of human TRPML2-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMucolipin-3(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50569846(CHEMBL4857820)
Affinity DataEC50:  8.50E+3nMAssay Description:Activation of human TRPML3-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed