BDBM50569837 CHEMBL4878570

SMILES ONC(=O)C1CCN(CC(O)COC(Cn2c3ccccc3c3ccccc23)Cn2c3ccccc3c3ccccc23)CC1

InChI Key InChIKey=OCVYWWSLZGQEHY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50569837   

TargetDNA (cytosine-5)-methyltransferase 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50569837(CHEMBL4878570)
Affinity DataIC50: 2.02E+3nMAssay Description:Inhibition of DNMT1 (unknown origin) using poly(dI-dC)-poly(dI-dC as substrate in presence of [3H-SAM] preincubated for 15 mins followed by substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50569837(CHEMBL4878570)
Affinity DataIC50: 930nMAssay Description:Inhibition of DNMT3A (unknown origin) using biotinylated DNA oligonucleotides as substrate in presence of [3H-SAM] preincubated for 15 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50569837(CHEMBL4878570)
Affinity DataIC50: 4.16E+3nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-peptide as substrate in preincubated for 15 mins followed by substrate addition and measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed