BDBM50569815 CHEMBL4873623

SMILES CCC(Oc1cccc(Cl)c1Cl)c1nc(N)nc(n1)N1CCN(C)CC1

InChI Key InChIKey=WBFUPJYWMYUSBO-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50569815   

Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50569815(CHEMBL4873623)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in HEK293 cells incubated for 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50569815(CHEMBL4873623)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]-LSD from human 5-HT6R expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50569815(CHEMBL4873623)
Affinity DataKi:  209nMAssay Description:Displacement of [3H]-Ketanserin from human 5-HT2A receptor expressed in CHO-K1 cells incubated for 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Monash University Malaysia

Curated by ChEMBL
LigandPNGBDBM50569815(CHEMBL4873623)
Affinity DataKi:  210nMAssay Description:Displacement of [3H]-Raclopride from human 5-HT2AR expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Monash University Malaysia

Curated by ChEMBL
LigandPNGBDBM50569815(CHEMBL4873623)
Affinity DataKi:  420nMAssay Description:Displacement of [3H]-Raclopride from human dopamine D2 receptor expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Monash University Malaysia

Curated by ChEMBL
LigandPNGBDBM50569815(CHEMBL4873623)
Affinity DataKi:  421nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Monash University Malaysia

Curated by ChEMBL
LigandPNGBDBM50569815(CHEMBL4873623)
Affinity DataKi:  520nMAssay Description:Displacement of [3H]-Raclopride from human 5-HT1AR expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Monash University Malaysia

Curated by ChEMBL
LigandPNGBDBM50569815(CHEMBL4873623)
Affinity DataKi:  5.20E+3nMAssay Description:Displacement of [3H]-5Carboxyamidotryptamine from human 5-HT7R expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Monash University Malaysia

Curated by ChEMBL
LigandPNGBDBM50569815(CHEMBL4873623)
Affinity DataKi:  5.20E+3nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7R expressed in human HEK293 cells incubated for 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed