BDBM50569797 CHEMBL4853116

SMILES CC1(C)C[C@H]2CN1c1nc(ccc1C(=O)NS(=O)(=O)c1cccc(NCCC2)n1)-n1ccc(OC[Si](C)(C)C)n1

InChI Key InChIKey=VXNBAFISXVKPSZ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50569797   

TargetCystic fibrosis transmembrane conductance regulator(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50569797(CHEMBL4853116)
Affinity DataEC50: <1.00E+3nMAssay Description:Potentiation of CFTR in primary human epithelial enteroid cells assessed as chloride transport in presence of forskolin by measuring membrane potenti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed