BDBM50569720 CHEMBL4848588

SMILES CC(C)(C)c1ccc(CN2CCS(=O)(=O)N(CCc3ccc(cc3)S(N)(=O)=O)C2)cc1

InChI Key InChIKey=JSPCHURBYBJNPX-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50569720   

TargetCarbonic anhydrase 12(Human)
Ege University

Curated by ChEMBL
LigandPNGBDBM50569720(CHEMBL4848588)
Affinity DataKi:  9.60nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 assessed as inhibition constant preincubated for 15 mins by measured for 10 to 100 secs by phen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCarbonic anhydrase 7(Human)
Ege University

Curated by ChEMBL
LigandPNGBDBM50569720(CHEMBL4848588)
Affinity DataKi:  30nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 assessed as inhibition constant preincubated for 15 mins by measured for 10 to 100 secs by pheno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandPNGBDBM50569720(CHEMBL4848588)
Affinity DataKi:  217nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandPNGBDBM50569720(CHEMBL4848588)
Affinity DataKi:  217nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 assessed as inhibition constant preincubated for 15 mins by measured for 10 to 100 secs by pheno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
Ege University

Curated by ChEMBL
LigandPNGBDBM50569720(CHEMBL4848588)
Affinity DataKi:  1.21E+3nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 assessed as inhibition constant preincubated for 15 mins by measured for 10 to 100 secs by pheno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Ege University

Curated by ChEMBL
LigandPNGBDBM50569720(CHEMBL4848588)
Affinity DataKi:  7.74E+3nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ege University

Curated by ChEMBL
LigandPNGBDBM50569720(CHEMBL4848588)
Affinity DataKi:  7.74E+3nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 assessed as inhibition constant preincubated for 15 mins by measured for 10 to 100 secs by pheno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed