BDBM50569709 CHEMBL4855465

SMILES NS(=O)(=O)c1ccc(cc1)N1CN(Cc2ccc(cc2)C(F)(F)F)CCS1(=O)=O

InChI Key InChIKey=JQMCOHBFOVQMRA-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50569709   

TargetCarbonic anhydrase 7(Human)
Ege University

Curated by ChEMBL
LigandPNGBDBM50569709(CHEMBL4855465)
Affinity DataKi:  34nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 assessed as inhibition constant preincubated for 15 mins by measured for 10 to 100 secs by pheno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandPNGBDBM50569709(CHEMBL4855465)
Affinity DataKi:  40nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandPNGBDBM50569709(CHEMBL4855465)
Affinity DataKi:  40nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 assessed as inhibition constant preincubated for 15 mins by measured for 10 to 100 secs by pheno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
Ege University

Curated by ChEMBL
LigandPNGBDBM50569709(CHEMBL4855465)
Affinity DataKi:  71nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 assessed as inhibition constant preincubated for 15 mins by measured for 10 to 100 secs by phen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
Ege University

Curated by ChEMBL
LigandPNGBDBM50569709(CHEMBL4855465)
Affinity DataKi:  290nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 assessed as inhibition constant preincubated for 15 mins by measured for 10 to 100 secs by pheno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Ege University

Curated by ChEMBL
LigandPNGBDBM50569709(CHEMBL4855465)
Affinity DataKi:  7.64E+3nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ege University

Curated by ChEMBL
LigandPNGBDBM50569709(CHEMBL4855465)
Affinity DataKi:  7.64E+3nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 assessed as inhibition constant preincubated for 15 mins by measured for 10 to 100 secs by pheno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed