BDBM50569538 CHEMBL4859010::US11452717, Compound TableB-1.48

SMILES O=C(NCc1cn[nH]c1)Nc1ccc(cc1)S(=O)(=O)c1ccccc1

InChI Key InChIKey=LVNBMTBXTMDFOT-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50569538   

TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

Curated by ChEMBL
LigandPNGBDBM50569538(CHEMBL4859010 | US11452717, Compound TableB-1.48)
Affinity DataEC50:  28nMAssay Description:Activation of human NAMPTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

Curated by ChEMBL
LigandPNGBDBM50569538(CHEMBL4859010 | US11452717, Compound TableB-1.48)
Affinity DataEC50: <100nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
Go to US Patent