BDBM50569522 CHEMBL4867843::US11452717, Compound TableB-1.19

SMILES CCOC(=O)c1ccc(NC(=O)NCc2c[nH]nn2)cc1

InChI Key InChIKey=BSQYMYJUZLPDDM-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50569522   

TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

Curated by ChEMBL
LigandPNGBDBM50569522(CHEMBL4867843 | US11452717, Compound TableB-1.19)
Affinity DataEC50:  7.75E+3nMAssay Description:Activation of human NAMPTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

Curated by ChEMBL
LigandPNGBDBM50569522(CHEMBL4867843 | US11452717, Compound TableB-1.19)
Affinity DataEC50: >2.00E+4nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
Go to US Patent